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SIRNA

MISSION® siRNA产品系列

Custom and Predesigned siRNA

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siRNA, siRNA混合库, 定制siRNA, 预设计siRNA, 高通量siRNA

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Antonis C Antoniou et al.
The New England journal of medicine, 371(6), 497-506 (2014-08-08)
Germline loss-of-function mutations in PALB2 are known to confer a predisposition to breast cancer. However, the lifetime risk of breast cancer that is conferred by such mutations remains unknown. We analyzed the risk of breast cancer among 362 members of
Fuhui Xu et al.
PloS one, 9(9), e106509-e106509 (2014-09-04)
Improved drought tolerance is always a highly desired trait for agricultural plants. Significantly increased drought tolerance in Arabidopsis thaliana (Columbia-0) has been achieved in our work through the suppression of ESKMO1 (ESK1) gene expression with small-interfering RNA (siRNA) and overexpression
Maria Dermit et al.
Developmental cell, 55(3), 298-313 (2020-11-11)
Translation of ribosomal protein-coding mRNAs (RP-mRNAs) constitutes a key step in ribosome biogenesis, but the mechanisms that modulate RP-mRNA translation in coordination with other cellular processes are poorly defined. Here, we show that subcellular localization of RP-mRNAs acts as a
Jieru E Lin et al.
Cancer research, 76(2), 339-346 (2016-01-17)
Obesity is a well-known risk factor for colorectal cancer but precisely how it influences risks of malignancy remains unclear. During colon cancer development in humans or animals, attenuation of the colonic cell surface receptor guanylyl cyclase C (GUCY2C) that occurs
Yanli Ma et al.
PloS one, 7(10), e47961-e47961 (2012-11-01)
Aflatoxin B1 (AFB1) is a potent carcinogen that can induce hepatocellular carcinoma. AFB1-8,9-exo-epoxide, one of AFB1 metabolites, acts as a mutagen to react with DNA and induce gene mutations, including the tumor suppressor p53. In addition, AFB1 reportedly stimulates IGF
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Long Oligos

Techniques for long oligo synthesis and purification offer superior quality unmatched by other suppliers.

Predesigned siRNA

Rosetta siRNA Design Algorithm optimizes siRNA sequences for reduced off-target effects and increased RNAi performance.

Custom Next-Gen Sequencing Oligos

Regardless of next-generation sequencing (NGS) platform, universal and index adapter sequences are required for the proper assembly of sample fragments.

Positive Control siRNA

MISSION Positive Control siRNA, validated for siRNA silencing experiments, saves time in gene silencing research.

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定制 cGMP 寡核苷酸

如果您计划进行分子诊断(MDx)商业化，开发实验室开发试验(LDT)，或进行治疗学临床前研究，最终的成品试剂盒、检测试剂或药品必须具有非凡的质量水平，符合严苛的监管或研究标准。

定制cGMP寡核苷酸将于2023年上市

如果您计划进行分子诊断(MDx)商业化，开发实验室开发试验(LDT)，或进行治疗学临床前研究，最终的成品试剂盒、检测试剂或药品必须具有非凡的质量水平，符合严苛的监管或研究标准。

Custom siRNA Duplex Plates

Use our synthetic, small interfering RNA (siRNA) duplex plates to identify gene function, elucidate pathways, and screen for potential new drug targets.

Custom siRNA

RNA interference via siRNA offers precise gene silencing, aiding gene function studies and drug target screening.

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